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Patient Death Casts Cloud Over Roche Emicizumab Hemophilia Trial

 
• By Alexandra Shimmings

The death of a patient during the HAVEN 1 study of Roche's investigational hemophilia product, emicizumab, may be nothing to panic about, but it is increasing concerns over its likely impact on the potential blockbuster drug's label.

Coagulation Factor VIII Protein
• Source: Shutterstock

A patient death in the Phase III HAVEN 1 study of Roche's investigational hemophilia A treatment, emicizumab (ACE-910), may have cast a shadow over the product's safety profile, but experts say there is no conclusive evidence that it was related to the drug. Even so, concerns are growing over the investigational drug's side effect profile.

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