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New AURA Lupus Data Bode Well For Aurinia's Voclosporin In Future Phase III

 
• By Emily Hayes

Long-term data from the AURA-LV study in lupus nephritis show voclosporin is superior to standard of care, raising expectations for future Phase III success.

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Additional data for Aurinia Pharmaceuticals Inc.'s voclosporin in the Phase IIb AURA-LV clinical trial show a much improved complete response rate for patients with lupus nephritis relative to the comparator arm of the trial after 48 weeks, boosting the company's stock and expectations for a positive result in Phase III.

Previously reported 24-week data also showed a significant response for lupus nephritis (LN) patients treated with voclosporin, but the 48-week results were so much better that Aurinia may amend its Phase III primary endpoint to capture complete response rates at the longer time point

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