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TG Celebrates High Risk CLL Data - But Cloud Looms From Rival Trial

 
• By Sukaina Virji

TG Therapeutics is savoring positive trial data on its investigational TG-1101 in high risk CCL - but that could be soured next year by a little known mid-stage trial of Imbruvica plus Rituxan.

Positive top line data for TG Therapeutics Inc.' Phase III GENUINE study of TG-1101 (ublituximab, a monoclonal antibody that targets CD20) plus Imbruvica (ibrutinib) versus Imbruvica alone in previously treated patients with high-risk r/r CLL were welcomed by analysts and investors alike, ensuring the company's share price almost doubled within a week.

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