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Sun Builds On Psoriasis Data But Can It Hold In Crowded Space?

 
• By Anju Ghangurde

Sun Pharma’s executive vice president, biologics and dermatology, Jesper Ostergaard Jensen, elaborates on some aspects of the recent encouraging data around the company’s late stage psoriasis asset, tildrakizumab. Jensen also tells Scrip that the firm is upbeat about its acne and photodynamic therapy products in the US.

Marathon runners
Sun Pharma's tildrakizumab faces a crowded competitive space • Source: Shutterstock

Sun Pharmaceutical Industries Ltd. has underscored the potential long-term efficacy of its late stage psoriasis asset, tildrakizumab, as part of recent new analyses from the Phase I and the pivotal Phase III clinical trials (reSURFACE 1 and 2) of the investigational IL-23p19 inhibitor.

The pivotal Phase III reSURFACE trial results presented to date are through week 64 and indicate “significantly improved” skin clearance in clinical trial participants using tildrakizumab, with a safety profile comparable to placebo. Data had previously shown that the targeted effects of tildrakizumab improved skin clearance in clinical trial participants with as few as two doses, with nearly two-thirds of patients achieving at least 75% skin clearance at week 12

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