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56 Biosimilars In Late-Stage Development Line Up To Challenge Top Biologic Drugs

 
• By Ian Schofield

Many key biologic drugs, including adalimumab, bevacizumab, rituximab and trastuzumab, are facing biosimilar competition from products that have been either filed or recently approved in Europe, and 56 biosimilars are now at a late stage of clinical development, according to Per Troein of QuintilesIMS.

Tooth wheel mechanism with DIFFERENT, SIMILAR letters
Biosimilars are increasing their market share in Europe • Source: Shutterstock

56 biosimilar products are in late-stage development at global level, 47 of which are in Phase III trials and nine at the pre-registration stage. The top diseases being targeted are autoimmune disease (27 of the late-stage 56 products) and oncology (24), followed by diabetes (four), respiratory disease (two) and others (three). 68 biosimilars are at the preclinical stage, 14 are in Phase I trials and three are in Phase II.

The figures were presented by Per Troein, vice-president strategic partners at QuintilesIMS, during the recent Medicines for Europe annual biosimilars conference in London. He said that “the leading biological products...

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