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Mite Trial Failure 'The Final Straw' As Circassia Ends Anti-Allergy Investing

 
• By Sten Stovall

Circassia has thrown in the towel on investing in anti-allergy vaccines and will focus now on respiratory activities, after its house dust mite allergy study missed its primary endpoints.

Woman scratching neck
Circassia exits from allergies • Source: Shutterstock

Hurdles facing those trying to develop new allergy vaccines have been underscored yet again by the failure of Circassia Pharmaceuticals PLC ’s potential house dust mite allergy immunotherapy in a Phase IIb field study which missed its primary endpoints, displaying instead a strong placebo effect that mirrored the biotech's previously failed cat allergy Phase III trial in June 2016.

The UK-based company says it is thus ending all anti-allergy investments to focus on its broader respiratory business, including the...

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