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Phase III Data For La Jolla's Angiotensin II Drug Leave Questions About Clinical Benefit

 
• By Emily Hayes

La Jolla's LJPC-501 meets primary blood pressure endpoint in the Phase III ATHOS-3 vasodilatory shock trial, but data suggest benefits may not translate into clinically meaningful improvements.

Full data from the Phase III ATHOS-3 Phase III study of La Jolla Pharmaceutical Co.'s synthetic angiotensin II drug LJPC-501 bode well for approval, but nevertheless raise questions about commercial value, some analysts say.

Cleveland Clinic anesthesiologist Ashish Kanna reported full data from the positive trial in the New England Journal of Medicine on May 21, following an earlier top-line release

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Pipeline Watch: Six Approvals And Thirteen Phase III Readouts

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