Lilly's Cyramza Expands Its RANGE With Bladder Cancer But OS Data Needed

Lilly's Cyramza has become the first product to show an improvement in progression-free survival in previously treated advanced bladder cancer, but the company is waiting to see an overall survival benefit before it takes the data to the regulators.

Eli Lilly & Co. 's anti-VEGF receptor 2 antibody, Cyramza (ramucirumab), has met the primary endpoint of progression-free survival in the Phase III RANGE study in advanced urothelial cancer, but any filings are unlikely to come before late next year.

Lilly expects that overall survival (OS) results would be required to expand the product's label – final OS results are...

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

Start your 7-day free trial
Explore trusted news, analysis, and insights
Access comprehensive global coverage
Enjoy instant access – no credit card required

Start Free Trial

Already a subscriber?

Sanofi/Orano Look To Next Steps After Phase II Radiotherapy Success

Oct 08 2025

• By Alaric DeArment

The companies announced positive Phase II results for AlphaMedix, a lead 212-based alpha emitter therapy for gastroenteropancreatic neuroendocrine tumors.

Psoriasis Submissions Iin The Bag, J&J Advances Icotrokinra Into Phase III For Ulcerative Colitis

Oct 08 2025

• By Kevin Grogan

The company has presented the full set of positive results from the Phase IIb ANTHEM-UC trial in the inflammatory bowel disease.

Hope Medicine Ready To Bring Potential First-in-Class Endometriosis Treatment Into Phase III

Oct 08 2025

• By Andrew McConaghie

The non-hormonal drug could be a big step forward in treating pain associated with the condition, but the Chinese company may still need a partner for its Phase III studies and eventual commercialization.

Biomea Plans To Advance Menin Inhibitor In Two Type 2 Diabetes Subgroups

Oct 07 2025

• By Joseph Haas

With 52-week Phase II data, struggling Biomea said it would go forward in insulin-deficient type 2 diabetes patients and those who had not achieved HbA1c goals on GLP-1 therapy.

Biomea Plans To Advance Menin Inhibitor In Two Type 2 Diabetes Subgroups

Oct 07 2025

• By Joseph Haas

With 52-week Phase II data, struggling Biomea said it would go forward in insulin-deficient type 2 diabetes patients and those who had not achieved HbA1c goals on GLP-1 therapy.