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Lilly's Cyramza Expands Its RANGE With Bladder Cancer But OS Data Needed

 
• By Alexandra Shimmings

Lilly's Cyramza has become the first product to show an improvement in progression-free survival in previously treated advanced bladder cancer, but the company is waiting to see an overall survival benefit before it takes the data to the regulators.

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• Source: Shutterstock

Eli Lilly & Co. 's anti-VEGF receptor 2 antibody, Cyramza (ramucirumab), has met the primary endpoint of progression-free survival in the Phase III RANGE study in advanced urothelial cancer, but any filings are unlikely to come before late next year.

Lilly expects that overall survival (OS) results would be required to expand the product's label – final OS results are not due until in mid-2018.

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