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Clovis's Rubraca Leapfrogs Rivals In Ovarian Cancer As ARIEL3 Hits

 
• By Alexandra Shimmings

Clovis Oncology is forging ahead with a filing for a maintenance indication for its PARP inhibitor Rubraca in a broad ovarian cancer population as new data from ARIEL3 blow the field wide open.

Mermaid
ARIEL seeks a new world of patients for Rubraca • Source: Shutterstock

Clovis Oncology Inc.'s PARP inhibitor Rubraca (rucaparib) has shown a benefit on progression-free survival in the ARIEL3 study in a wider range of ovarian cancer patients than its current label covers. The company will use the data for an sNDA application within the next four months for a second-line and later maintenance treatment indication for all women with platinum-sensitive ovarian cancer who have responded to their most recent platinum therapy.

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