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Antibiotic Pipeline Profile: Balancing Broad Spectrum And Limited Use

 
• By Bridget Silverman

Broad spectrum antibiotic candidates for hospital use dominate the late-stage pipeline under the US FDA's Qualified Infectious Disease Product (QIDP) program, despite efforts to target limited populations of patients and pathogens.

Bacterias 3D rendering

Broad spectrum systemic antibiotics for hospitalized patients will likely continue to account for most of the novel agents approved under the Qualified Infectious Disease Product (QIDP) designation for the near future, according to data from Scrip sister publication The Pink Sheet's FDA Performance Tracker.

Antibiotic Pipeline Series

This is the second article in a series about the antibiotic development pipeline.

For the first article regarding progress and challenges following the US FDA's establishment of the QIDP program, see:

Antibiotics Pipeline Is Lively, But Sponsors Are Fragile

Watch for two more articles in the series regarding narrow-spectrum antibiotics and targeted delivery.

Broad spectrum agents remain the best option for acutely ill patients who cannot wait to begin treatment while bacteria are...

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