Without J&J, Capricor Plans To Advance Progenitor Cell Therapy In DMD

California biotech says it will move forward with knowledge and expertise gained through the failed partnership. Capricor hopes to re-partner CAP-1002 for cardiovascular indications, while continuing the candidate’s DMD development itself.

Johnson & Johnson's departure from a partnership with Capricor Therapeutics Inc. on the cardiac progenitor cell therapy CAP-1002 means the biotech will miss out on a significant revenue opportunity, but the company thinks it remains well positioned to move the candidate forward in a smaller indication, cardiomyopathy associated with Duchenne muscular dystrophy.

Los Angeles-based Capricor revealed July 6 that Janssen Biotech Inc. had elected not to take an option under an agreement signed in 2014 to advance CAP-1002 (allogeneic cardiosphere-derived cells) as a regenerative therapy for patients who sustain cardiac scar tissue following a heart attack. [See Deal] The J&J affiliate had paid $12

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