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Merck's Keytruda Gets Benefit Of Doubt, Despite Failing in Head & Neck

 
• By Emily Hayes

Prior PD-1 failures after accelerated approval include Roche's Tecentriq in bladder cancer.

Mouth Anatomy

Merck & Co. Inc.'s PD-1 inhibitor Keytruda has failed to show a survival benefit in the KEYNOTE-040 study of head and neck cancer, which was meant to confirm an accelerated approval, but the company does not foresee a labeling change.

Merck sais July 24 that median overall survival (OS) for Keytruda in the study of recurrent or metastatic head and...

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