Post-MYSTIC, Bristol Renews CTLA-4 Vows, But Is "Not Wedded" In Lung Cancer

Company distances its CheckMate 227 CTLA-4/PD-1 combo study from AstraZeneca's doomed MYSTIC trial, noting big differences, but also makes it clear that its options are very open for monotherapy and chemo combos in first-line lung cancer.

T-cells attacking cancer_1200x675

Bristol-Myers Squibb Co. talked up its commitment to the CTLA-4 checkpoint target, accentuating its strong qualities and track record, while also saying it is "not wedded" to the CTLA-4/PD-1 combination in lung cancer and has lots of options, during its second-quarter earnings call July 27.

More from R&D

More from Scrip

Will Irish Eyes Still Be Smiling When Trump Tariffs Hits Pharma?

 
• By 

The US president's most recent comments suggest tariffs on pharma are imminent and Ireland has the most to lose.

China Deal-Making Matures As Foreign Partners Derisk Asset Acquisition

 
• By 

Chinese biopharma companies’ alliance strategies are transitioning from immediate cash needs to more strategic management of portfolios, as MNCs continue to hunt for derisked assets.

Cartesian Maps Out CAR-T Strategy With Simpler Logistics In Mind

 

The company announced positive Phase IIb data for Descartes-08 in myasthenia gravis, with especially strong efficacy among patients without prior biologic treatment.