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FibroGen Hails 'Milestone' IPF Data, Phase III And Partners Beckon

 
• By Alexandra Shimmings

Phase II data for FibroGen's first-in-class therapy for idiopathic pulmonary fibrosis panrevlumab has sent its shares soaring and could have potential partners scrambling.

Spitfire
Chocks Away - Pipeline Progress For FibroGen • Source: Shutterstock

FibroGen Inc. appears to have a potential blockbuster on its hands with its anti-connective tissue growth factor (CTGF) antibody pamrevlumab (FG-3019) after Phase II data suggested its potential as a monotherapy and possibly in combination with current treatments for idiopathic pulmonary fibrosis, a disease which has a poorer prognosis than many cancers.

The data suggest that as a monotherapy the drug produces a similar reduction in the rate of disease progression as currently marketed therapies – nintedanib (Boehringer Ingelheim's Ofev) and pirfenidone...

Pamrevlumab is a fully-human monoclonal antibody that inhibits the activity of connective tissue growth factor (CTGF), a common factor in chronic fibrotic and proliferative disorders characterized by persistent and...

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