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Another Opdivo Disappointment For BMS, This Time In Kidney Cancer

 
• By Mandy Jackson

Bristol-Myers Squibb's Opdivo plus Yervoy in first-line RCC did not achieve statistical significance in terms of progression-free survival versus Sutent, but overall survival data aren't available yet.

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Bristol-Myers Squibb Co. reported once again that the combination of its blockbuster PD-1 inhibitor Opdivo (nivolumab) and CTLA-4 inhibitor Yervoy (ipilimumab) did not achieve statistical significance in a Phase III clinical trial – at least in terms of progression-free survival – but the ongoing first-line renal cell carcinoma (RCC) trial still could yield significant results in overall survival.

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