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Inside The Lupus Pipeline: Reasons For Optimism

 
• By Jessica Merrill

Several drugs for systemic lupus erythematosus (SLE) and lupus nephritis are in mid-to-late stage development, which could pave the way for new treatments for a disease with few options. Experts say they are energized by the amount of investment in lupus R&D.

Medecine concept - Blackboard with text "Lupus", book, pills and stethoscope on blue wooden background

The lupus drug development landscape is showing signs of renewal after a string of disappointments, with several new drugs for systemic lupus erythematosus (SLE) and lupus nephritis (LN) moving through mid-to-late stage development. Big pharmas like AstraZeneca PLC, Johnson & Johnson and Roche's Genentech Inc., as well as smaller companies like Aurinia Pharmaceuticals Inc. and Corbus Pharmaceuticals Holdings Inc. are pushing ahead in lupus, despite considerable challenges.

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