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Novartis Beats CAR-T Competitors To The Pricing Punch With Kymriah Approval

 
• By Mandy Jackson

Novartis got a leg up on its competition Aug. 30 with an earlier-than-expected approval for Kymriah in pediatric ALL, ending the CAR-T pricing mystery with its $475,000 price tag, which the company is positioning as a relative bargain.

Destruction of leukaemia cell, conceptual image. 3D illustration which can be used to illustrate blood cancer treatment

Novartis AG was the first company to submit a chimeric antigen receptor T cell (CAR-T) therapy for US FDA consideration and now with Kymriah (tisagenlecleucel) it is the first to win approval for the game-changing treatment modality, and thus set the pricing bar for competing CAR-T products.

The FDA approved Kymriah on Aug. 30 – about a month earlier than the Oct. 3 user fee date – for the treatment of pediatric and young adult patients (up to age 25) with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or has relapsed after at least two prior lines of therapy

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