Success in a second Phase III trial of Motif Bio PLC's lead product positions the company for its first filing application for its novel antibiotic iclaprim in acute bacterial skin and skin structure infections (ABSSSI). The product, however, has been brought before the regulators before, and success this time would be the culmination of a long and chequered development story.
Iclaprim was set on its way to final success when positive results from the first Phase III trial REVIVE-1 were...