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Janssen's Darunavir-Based Single-Tablet Effective In Late-Stage Switching Study

 
• By John Davis

Switching to a once-daily single tablet containing four constituents that is centered on Janssen's protease inhibitor darunavir was non-inferior to other combination therapies after 48 weeks of therapy, say researchers running the Phase III EMERALD study.

Glue
Adherence to a HIV regimen can reduce resistance development • Source: Shutterstock

Johnson & Johnson may be taking a back seat in the hepatitis C market, but it is looking more competitive in the HIV/AIDS sector, where just-released top-line 48-week efficacy and safety data from the Phase III EMERALD study show a lack of virologic rebound and similar virologic suppression and safety associated with the company’s darunavir-based once-daily single-tablet regimen to with multi-pill therapies being taken by control patients.

In announcing the results, J&J's Janssen Pharmaceutica NV and AIDS researchers highlighted the likely better adherence of patients to...

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Pipeline Watch: Eight Approvals And Ten Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.

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• By Joseph Haas

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