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What Was On Hold Is New Again As Impact Raises $22.5m For Fedratinib

 
• By Mandy Jackson

Medicxi-funded Impact Biomedicines gave Sanofi a stake in the start-up to acquire fedratinib and bring the JAK2 inhibitor, which was placed on a clinical hold in 2013, to patients who are out of options.

Businessman looking through a magnifying glass to documents

It's a straightforward, roundabout story: Impact Biomedicines acquired fedratinib from Sanofi for a minority stake in the start-up, convinced the US FDA to remove a clinical hold on the JAK2 inhibitor that's completed a Phase III clinical trial in myelofibrosis, and raised $22.5m to seek approval.

The roundabout part of the straightforward story is that Impact's CEO John Hood was the chief executive at TargeGen Inc., which Sanofi purchased in 2010 to acquire fedratinib

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