Silence Seeks Share Of Alnylam RNAi Success In Legal Action

The UK firm believes its siRNA stabilisation chemistryis represented in several late-stage RNAi studies and that market leader Alnylam requires a license that could have a material impact on Silence's market capitalization.

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The promise of RNAi is close to providing a marketed product • Source: Shutterstock

As Alnylam Pharmaceuticals Inc. finalizes plans to file the first RNA interference therapeutic, patisiran, the UK's Silence Therapeutics PLC has begun the next phase of its legal moves to claim intellectual property rights and a share in any success of this and other drugs in this closely-watched field.

In July, Silence launched an action in the UK High Courts of Justice (Patents Court) against US-based Alnylam, its UK...

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