Gilead/Kite Pricing For Yescarta Undercuts Novartis's CAR-T Kymriah

Gilead's newly acquired CAR-T therapy Yescarta, developed by Kite Pharma, won FDA approval for certain B cell lymphomas on Oct. 18 and the company set its price $102,000 below Novartis's competing therapy Kymriah, which was approved in a small pediatric leukemia indication.

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Gilead Sciences Inc. paid $11.9bn for Kite Pharma Inc. in a deal that closed earlier this month and will soon reap rewards from that long-awaited transaction following the Oct. 18 US FDA approval of Yescarta (axicabtagene ciloleucel), but its return on investment won't come at a market-leading price.

The autologous CD19-targeting chimeric antigen receptor T cell (CAR-T) therapy was approved for adults with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy and Gilead priced the one-time treatment at $373,000. While that's 21

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