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Behind The NASH Leaders, Pursuers Already Anticipating Second-Wave Improvements

 
• By Joseph Haas

Privately held Cirius and NGM and big pharma Bristol-Myers Squibb are in Phase II for NASH with programs also working to validate non-invasive biomarkers for diagnosis, prognosis and treatment impact.

scientists doing lab research on digital screen

The unmet need in non-alcoholic steatohepatitis (NASH) has prompted numerous companies to aggressively pursue the opportunity. And while there is fierce competition to be first to market, the companies trailing the vanguard of drug development are aiming to improve on that first wave.

There are four companies already in Phase III in NASH – Intercept Pharmaceuticals Inc., Genfit SA, Allergan PLC and Gilead Sciences Inc. – and 19 others that have advanced at least to Phase II in the fatty liver disease, according to Biomedtracker

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