End Of The Line For AstraZeneca’s Tralokinumab In Asthma

Another Phase III failure looks likely to spell the end for AstraZeneca’s tralokinumab in severe uncontrolled asthma. The company’s eyes are now firmly fixed on benralizumab.

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AstraZeneca PLC’s anti-interleukin-13 (IL-13) human monoclonal antibody tralokinumab has failed in two further Phase III studies (STRATOS 2 and TROPOS), leaving the company now banking on benralizumab to help offset generic pressure to its asthma franchise.

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