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AbbVie's Alzheimer's Efforts Voyage Into AAV-Targeted Tau Antibodies

 
• By Joseph Haas

Collaboration between Voyager and AbbVie will attempt to produce a single-administration gene therapy targeting tau protein, using adeno-associated vector technology to pass the blood-brain barrier.

MR image of Human brain

AbbVie Inc.and Voyager Therapeutics Inc. are collaborating on an Alzheimer's disease program that would create a single-administration gene therapy delivering a monoclonal antibody targeting tau protein into the patient's central nervous system via a targeting mechanism using adeno-associated vector (AAV) technology.

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