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Biogen, AbbVie Withdraw Struggling MS Drug Zinbryta Due To Safety Issues

 
• By Joseph Haas

Antibody was approved in the US with a liver safety warning while EU regulators recently limited the drug's use. Now, EMA has begun an urgent review of reports of inflammatory brain disorders related to Zinbryta.

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There were indications during Biogen Inc.'s most recent earnings call in January that it was getting ready to pull the plug on struggling multiple sclerosis drug Zinbryta (daclizumab), but with the European Medicines Agency revealing it's begun an "urgent review" of cases of inflammatory brain disease in patients who've taken the drug, the decision became more clear-cut.

Biogen and its US marketing partner AbbVie Inc. announced on March 2 that they were voluntarily withdrawing worldwide marketing authorizations for Zinbryta, an antibody that targets both interleukin-2 (IL-2)...

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