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Enteric Fever, Plague Vaccines From Synthetic Biology Firm Near Clinical Studies

 
• By John Davis

The oral administration of synthetic thermostable vaccines that use a bacterial vector could enter clinical studies in 2019, funded by VCs interested in their use in emerging markets, where endemic and childhood diseases could yield to the new approach.

Thermostate
Thermostable vaccines will be less costly to distribute in emerging markets • Source: Shutterstock

Phase I clinical studies of Prokarium's two novel oral thermostable vaccines, against enteric fever (typhoid plus paratyphoid) and plague, are expected to start in 2019, says Ted Fjallman, CEO of the UK synthetic biology company.

A third vaccine, against Chlamydia, may not be far behind, following the recent completion of a $10m financing for Prokarium that involved new venture capital (VC) investors from Saudi Arabia and South Korea, as well as the

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Finance Watch: Deerfield Closes $600m-Plus VC Fund; Gates Speeds Up Health Investments

 
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Finance Watch: Deerfield Closes $600m-Plus VC Fund; Gates Speeds Up Health Investments

 
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