Seattle Genetics Says Adcetris Sets New Standard In Frontline Lymphoma

The market for a new FDA-approved indication in frontline classical Hodgkin lymphoma could be worth $650m to $750m, some analysts say.

Monomethyl auristatin E (MMAE, vedotin), the cytotoxic payload of brentuximab vedotin antibody-drug conjugate. Atoms are represented as spheres with conventional color coding: hydrogen (white), etc
Seattle Genetics' antibody drug conjugate Adcetris combines an antibody and cytotoxic payload of monomethyl auristatin E (depicted above) targeted at CD30 on lymphoma cells.

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