Weak Rova-T Data May Imperil AbbVie's Larger Cancer Ambitions

22 Mar 2018

Analysts already were skeptical about AbbVie's $5bn peak earnings projections for the ADC, but now some wonder if so-so data in third-line small cell lung cancer threaten Rova-T's viability for approval.

Render illustration of Clinical Trial title on medical documents

AbbVie Inc. avoided calling the Phase II TRINITY data it unveiled March 22 for rovalpituzumab tesirine (Rova-T) in small cell lung cancer a failure, but market analysts took no such precautions, with one saying the unconvincing data might "unravel AbbVie's oncology strategy."

The dire prognosis came from Leerink Partners analyst Geoffrey Porges, but he wasn't alone in seeing the unimpressive data for Rova-T as bad news for AbbVie's oncology plans. Sanford Bernstein...

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