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QUADRA Supports Broader Use For Tesaro's PARP Inhibitor Zejula

 
• By Emily Hayes

Study in late-line use of heavily pretreated ovarian cancer may bring labeling closer in line with competitors, yet with limited commercial impact, analysts say.

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Tesaro Inc.'s QUADRA study supports a supplemental NDA filing for the PARP inhibitor Zejula (niraparib) in the second half of the year for a biomarker-selected subset of heavily pretreated ovarian cancer patients, the company said in releasing top-line results of the trial April 24.

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Camzyos nHCM Failure Could Open Door To Threat From Cytokinetics’ Aficamten

 
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Camzyos nHCM Failure Could Open Door To Threat From Cytokinetics’ Aficamten

 
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BMS’s Phase III ODYSSEY-HCM study did not show statistical significance for either of its two primary endpoints.