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Allergan's Ubrogepant Succeeds In Second Acute Migraine Phase III Study

 
• By Mandy Jackson

The company intends to seek US FDA approval in the first half of 2019 for its CGRP inhibitor and believes that liver toxicity previously associated with oral drugs in this class are not a problem for its candidate ubrogepant.

Human brain illustrated with millions of small nerves - Conceptual 3d render

Allergan PLC had its confidence in the oral CGRP inhibitor ubrogepant confirmed when the drug succeeded in a second Phase III clinical trial in the treatment of acute migraine headaches, justifying a submission to the US FDA in the first half of 2019.

The calcitonin gene-related peptide (CGRP) inhibitors in late stages of development are chasing a market that hasn't had a new therapy approved in more than a decade, but will compete with generic triptans for payers' attention

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