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New Ways to Attack Atopic Dermatitis: Realm Expects POC Next Quarter

 
• By John Davis

Realm Therapeutics is evaluating a substance derived from insights into innate immunity that has potential as an immunomodulator in various dermatological disorders, including atopic dermatitis and acne, with proof-of-concept (POC) expected in the third quarter.

Prof of Concept
• Source: Shutterstock

Top-line results from a Phase II study of Realm Therapeutics' hypochlorous acid-containing lead product, PR022, in atopic dermatitis, are expected in the third quarter of 2018, and if positive should alleviate the disappointment felt when another of its lead products, PR013, failed in a Phase II study reported in March 2018.

"PR013 was being evaluated in allergic conjunctivitis, with a study design and immunologic pathology that were different from those involved...

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Pipeline Watch: Seven Approvals And Five Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.