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Phase III Beckons For A Short-Course Seasonal Allergic Rhinitis Jab

 
• By John Davis

A marketing approval for a seasonal allergic rhinitis vaccine from Allergy Therapeutics has moved nearer with positive top-line Phase II results that define the dose to be used in a Phase III study.

Grass
Various grasses produce large quantities of allergenic material • Source: Shutterstock

Considering the setbacks suffered by allergy product developers over the past several years, Allergy Therapeutics PLC executives most likely gave a sigh of relief when a new Phase II dose-ranging study with its candidate grass allergy product concluded with positive top-line results.

The study, G205, established a "highly statistically significant" dose-response relationship for its grass-modified allergen tyrosine absorbed (MATA) monophosphoryl lipid A (MPL) candidate for preventing grass-pollen induced seasonal allergic rhinitis, and a dose

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Pipeline Watch: Thirteen Approvals And Ten Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.