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Esperion Posts Positive Phase III Bempedoic Acid Results, But Future Fixed-Dose Data Are Key

 
• By Mandy Jackson

Esperion reported positive results from the third of five Phase III studies expected to read out this year, but data for a bempedoic acid/ezetimibe fixed-dose combo expected in August may be the key to the drug's commercial future.

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Esperion Therapeutics Inc.'s latest Phase III results for bempedoic acid in statin-intolerant patients with atherosclerotic cardiovascular disease (ASCVD) or at high risk for ASCVD met the LDL cholesterol-lowering primary endpoint and, importantly, didn't raise any new safety questions.

However, the data that may be most important for the oral therapy's commercial future aren't expected until August, when Esperion plans to disclose the first Phase III results for its...

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