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As A New Rival Approaches, PARP Makers Look To Carve Out Their Niche

 
• By Jessica Merrill

The US FDA has granted priority review for Pfizer's talazoparib, which would be the fourth PARP inhibitor on the market, though only the second for breast cancer behind Lynparza. Pfizer has a long-term eye on a combination of talazoparib with its PD-L1 inhibitor Bavencio, Oncology CMO Rothenberg told Scrip at ASCO. 

Priority letters

With Pfizer Inc. nearing the market with its polyl (ADP-ribose) polymerase inhibitor talazoparib, the PARP class is starting to get crowded – and sponsors are looking to carve out niche sections of the market, as executives explained to Scrip at the recent American Society of Clinical Oncology annual meeting.

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