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Migraine Drug Atogepant Delivers Good News When Allergan Needs It Most

 
• By Mandy Jackson

Oral CGRP inhibitor atogepant delivers strong Phase IIb/III results in episodic migraine prevention less than a week after activist investors went public with their push for a management shakeup to reverse Allergan's falling stock price.

Human brain illustrated with millions of small nerves - Conceptual 3d render

Allergan PLC's ubrogepant has been one of few bright spots during a period in which the company's stock has been in decline, so positive Phase IIb/III results for the follow-on CGRP inhibitor atogepant in episodic migraine comes as an opportune boost as the company pushes back against a pair of activist investors.

Ubrogepant, the firm’s lead CGRP inhibitor, will be submitted for US FDA approval for in the first half of 2019 for acute treatment of migraine headaches as they occur. Allergan must conduct another Phase III trial for atogepant before it will be submitted to the regulator

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Pipeline Watch: Thirteen Approvals And Ten Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.