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Eight Pivotal Trial Read-Outs Expected In Q3

 
• By Alexandra Shimmings

A number of pivotal studies are expected to report top-line data in the third quarter. Here, with the help of Informa Pharma's Biomedtracker, we take a look at eight of those likely to be major catalysts for their sponsors.

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Eight Q3 Trial Read-Outs

We have identified eight key trials expected to read out by the end of September 2018. Click on the item to jump straight to the details

RedHill Biopharma Ltd. is in August 2018 expected to report unblinded top-line results from the Phase III MAP US study of RHB-104, an oral antibiotic combination therapy containing rifabutin, clarithromycin and clofazimine. The product is under development for the potential treatment of Mycobacterium avium subspecies paratuberculosis (MAP) infection, which may be a disease-promoting factor in Crohn's disease. The international study in moderate to severely active Crohn’s disease has a primary endpoint of disease remission, defined as Crohn's Disease Activity Index (CDAI) value of less than 150 at week 26.

Two pre-planned analyses by an independent data and safety monitoring board have recommended its continuation. Analysts at Biomedtracker said blinded...

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Sjögren’s Success For Ianalumab Shores Up Novartis’s Pipeline-In-A-Product Plans

 
• By Alexandra Shimmings

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Pipeline Watch: Five Approvals And Two Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.