Yuhan Licenses Out Degenerative Disc Therapy To Spine Despite Earlier Trial Failure

South Korean pharma firm licenses out to US venture Spine Biopharma novel peptide drug for degenerative disc disease YH14618, despite a Phase II failure and trial halt in 2016.

3D spinal cord
YUHAN'S DISC DISEASE CANDIDATE LICENSED TO SPINE • Source: Shutterstock

Yuhan Corp. has licensed out its investigative degenerative disc therapy YH14618 to US-based Spine Biopharma LLC in a deal worth up to $218m plus sales royalties, reviving the compound after the leading South Korean pharma company halted clinical development after failure in a Phase II Korean study in 2016.

Under the new agreement, Spine Biopharma will proceed with development, approval, manufacturing and commercialization of the compound in global markets, while Yuhan will retain its sales rights in South Korea. Yuhan will receive $650,000 upfront and $217

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