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IMpower132 Casts More Doubt On Roche's Tecentriq In First-Line NSCLC

 
• By Emily Hayes

The lack of significant overall survival benefit in IMpower132 may be related to PD-L1 expression – though the dataset is incomplete – or the higher dose of chemo used in the trial.

Roche

Updated results from Roche's pivotal IMpower132 study cast more doubt about Tecentriq's ability to compete with Merck & Co. Inc.'s Keytruda in first-line non-small cell lung cancer (NSCLC).

Results from the IMpower132 study of Tecentriq in first-line NSCLC and the IMpower133 study of first-line small-cell lung cancer (SCLC) were presented at the International Association for the Study of Lung Cancer

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