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ECHELON-2 Ushers In Another New Adcetris Indication For Seattle Genetics

 
• By Mandy Jackson

The combination of Adcetris with chemotherapy improved progression-free and overall survival in peripheral T-cell lymphoma. Filing is expected soon, and approval will help the product reach blockbuster status.

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Seattle Genetics Inc. and Takeda Pharmaceutical Co. Ltd. reported top-line results on Oct. 1 for Adcetris (brentuximab vedotin) from the Phase III ECHELON-2 clinical trial in previously untreated CD30-expressing peripheral T-cell lymphoma (PTCL), showing an improvement in survival that may lead to a sixth indication for the product.

Seattle Genetics CEO Clay Siegall couldn't provide specifics about the timing of a supplemental biologics license application (sBLA) submission to the US FDA, but told Scrip the company is "working at top speed to get this done

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