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ECHELON-2 Ushers In Another New Adcetris Indication For Seattle Genetics

 
• By Mandy Jackson

The combination of Adcetris with chemotherapy improved progression-free and overall survival in peripheral T-cell lymphoma. Filing is expected soon, and approval will help the product reach blockbuster status.

Closed up finger on keyboard with word CLINICAL TRIALS

Seattle Genetics Inc. and Takeda Pharmaceutical Co. Ltd. reported top-line results on Oct. 1 for Adcetris (brentuximab vedotin) from the Phase III ECHELON-2 clinical trial in previously untreated CD30-expressing peripheral T-cell lymphoma (PTCL), showing an improvement in survival that may lead to a sixth indication for the product.

Seattle Genetics CEO Clay Siegall couldn't provide specifics about the timing of a supplemental biologics license application (sBLA) submission to the US FDA, but told Scrip the company is "working...

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