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Darzalex Excites As Potential Grows In Multiple Myeloma

 
• By John Davis

Positive top-line results from the MAIA study of daratumumab as a front-line treatment for multiple myeloma highlights the future sales growth potential of Genmab/J&J's CD38-targeted antibody, which could become the market leader in the sector in the next five years.  

Multiple myeloma
Characteristic Cytology Changes In Multiple Myeloma • Source: Shutterstock.

Positive top-line results from the Phase III MAIA study of Genmab AS's MAb, daratumumab, in combination with lenalidomide (Celgene Corp.'s Revlimid) and dexamethasone for the front-line treatment of multiple myeloma, announced Oct. 29, did not go unnoticed by investors.

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Seven Up For Sanofi and Regeneron With Dupixent CSU Approval

 
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Camzyos nHCM Failure Could Open Door To Threat From Cytokinetics’ Aficamten

 
• By Alaric DeArment

BMS’s Phase III ODYSSEY-HCM study did not show statistical significance for either of its two primary endpoints.

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Henlius In David Versus Goliath Race With Pfizer For First PD-L1 ADC

 
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While Henlius Biotech’s PD-L1-targeting antibody-drug conjugate HLX43 is struggling to catch up with Pfizer’s PF-08046054, the global frontrunner in the space, a key differentiation of the China-originated asset could lie in PD-L1-negative patients.

AstraZeneca Logs Japan Growth Despite Price Cuts

 
• By Lisa Takagi

AstraZeneca logs growth in Japan despite a big reimbursement price cut for one of its top sellers and expects 40 approvals in the country over the next six years.

Camzyos nHCM Failure Could Open Door To Threat From Cytokinetics’ Aficamten

 
• By Alaric DeArment

BMS’s Phase III ODYSSEY-HCM study did not show statistical significance for either of its two primary endpoints.