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Alligator CEO Discusses Pipeline Additions, Milestone Expectations And The IO Deal Landscape

 
• By Jo Shorthouse

Alligator Bioscience’s Per Norlen discusses the latest addition to its pipeline, a first-in-class bispecific tumor-localized antibody targeting the checkpoint inhibitor CTLA-4.

Video interview
• Source: Shutterstock

Speaking to Scrip on the sidelines of BIO-Europe in Copenhagen Alligator Bioscience AB’s CEO, Per Norlen, described the latest addition to the small Swedish cancer specialist’s pipeline, a bispecific antibody, ATOR-1144, which is a dual immune activator targeting CTLA-4 and GITR.

ATOR-1144 works through several pathways, including activation of T-cells, depletion of regulatory T-cells, and activation of NK cells, for enhanced tumor cell killing. Based on its mode of action, ATOR-1144...

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