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Roche/Abbvie's Venclexta Outshines Agios IDH Inhibition In AML At ASH

 
• By Emily Hayes

Clinicians weigh in on updated data presented at ASH in frontline acute myeloid leukemia, but caution that it is difficult to compare across clinical trials.

Acute myeloid leukemia a 3d-Render

Updated data for Roche/AbbVie Inc.'s BCL-2 inhibitor Venclexta in frontline treatment of acute myeloid leukemia looks robust – perhaps threatening Agios Pharmaceuticals Inc.'s IDH1/2 inhibitors Idhifa and Tibsovo – but clinical experts caution against comparing the two mechanisms, particularly without randomized data.

New data on all three drugs was presented at the American Society of Hematology (ASH)

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