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Lilly And AC Immune Partner On A Small Molecule With Potential In Alzheimer's Combinations

 
• By Jessica Merrill

Eli Lilly signed a licensing deal to develop a tau aggregation inhibitor small molecule for Alzheimer's disease – a drug that works differently from existing antibodies and could offer potential in combination regimens. AC Immune CEO Andrea Pfeifer talked to Scrip about the deal.

Puzzle

Eli Lilly & Co. has partnered with the Swiss neurodegenerative disease specialist AC Immune SA to develop tau-aggregation inhibitors, which are small molecules that could offer big potential as combination therapies with amyloid-beta antibodies. Combination therapy is where the industry increasingly is interested in going in Alzheimer's disease as clinical trial failures for various monotherapies pile up.

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