There were a lot of outliers in the US market for drug developer initial public offerings in 2018, including the biggest-ever biopharmaceutical IPO, but on average the returns on these investments were negative by the end of the year.
While 67 biopharma companies managed to launch IPOs in the US in 2018, 41 of these firms were trading below their offering prices as of Dec. 31, bringing the average return to -7.5% (see table below). That's a significant drop from the average of 0.3% for the 61 companies that went public last year as of Oct. 31
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