AbbVie’s Downward Humira Guidance Worries Analysts

Decreasing Humira’s ex-US sales guidance for the second time in three months caught significant attention, as AbbVie now expects 30% revenue erosion for its top-seller outside its home market.

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Much of the attention coming out of AbbVie Inc.'s earnings call Jan. 25 was focused on the company's reduction of ex-US revenue estimates for top-seller Humira (adalimumab) for the second time in recent months due to the impact of biosimilar competition – raising concerns that the impact of US biosimilars will be greater than AbbVie has suggested.

For the full year 2018, Humira grew 7.4% growth year-over-year to $19.94bn. Broken down, the autoimmune stalwart’s US sales of...

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