Modus CEO On Its Plans For An At-Home Injectable For Sickle Cell Crises

Modus Therapeutics has begun a Phase I study with subcutaneously administered sevuparin. Its CEO says this new formulation of its lead asset has the potential to be self-administered by sickle cell disease patients at home for the treatment of vaso-occlusive crises.

SickleCell
No therapies yet exist to treat painful crises, the hallmark of Sickle Cell Disease • Source: Shutterstock

Sickle cell disease-focused Modus Therapeutics AB has begun a Phase I dosing study in the US to assess the safety and tolerability of injecting the Swedish biotech’s lead asset sevuparin, the aim being to provide sickle cell patients with a non-opioid, therapy that can be dosed at home, rather intravenously in hospital, the group's CEO told Scrip.

The Phase I trial studying subcutaneously-administered sevuparin is being conducted in Florida in a hospital setting.

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