Novartis, Zurich University Spin-out Anaveon Tackles IL-2 Challenges With Fresh Funds

Syncona and Novartis Venture Fund have invested CHF35m in Anaveon, which reckons it can overcome the toxicity and half-life limitations of the cytokine interleukin-2 to enhance the body’s immune response to tumors.

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Andreas Katopodis (l) and Onur Boyman (r) • Source: Shutterstock

Only a little over a year after its founding, Anaveon has completed a CHF35m series A financing to advance selective interleukin-2 (IL-2) receptor agonists from preclinical studies into the clinic.

Set up by two immunotherapy experts, Onur Boyman, professor and chair in the department of immunology at the University of Zurich, and Andreas Katopodis, formerly director of the autoimmunity, transplantation and inflammation group in the Novartis Institutes for BioMedical Research (NIBR), Anaveon aims to develop compounds to

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