Dermira Inc.’s Phase IIb data for its IL-13 inhibitor lebrikizumab in atopic dermatitis showed efficacy across three dosing regimens, with a profile similar to market leader Dupixent. Now, the company hopes to initiate a Phase III study by year’s end that could set up the therapy with a dosing-convenience advantage compared to Sanofi/Regeneron Pharmaceuticals Inc.’s IL-4/IL-13 receptor antagonist.
Dermira’s Lebrikizumab Data Set Up Atopic Dermatitis Showdown With Dupixent
Dermira hopes to move into Phase III quickly with IL-13 inhibitor lebrikizumab, looking at monthly dosing in the maintenance setting. Efficacy in Phase IIb appears similar to Sanofi/Regeneron’s Dupixent.
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Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.
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