Cyclerion Readies For Readouts In Sickle Cell, Other Rare, Serious Diseases This Year

Spun out from Ironwood with a $175m financing, Cyclerion added Bayer and Shire veteran Andreas Busch to its management team as Chief Innovation Officer as it awaits a trio of Phase II data readouts coming this year for its sGC stimulators.

Sickle-Cells

Officially spun out of Ironwood Pharmaceuticals Inc., Cyclerion Therapeutics Inc. is recruiting new management experienced in both rare diseases and large indications, and gearing up for readouts from key programs in sickle cell disease, heart failure with preserved ejection fraction (HFpEF) and diabetic nephropathy.

Cambridge, Mass.-based Cyclerionofficially launched operations April 1 when its tax-exempt spinout from Ironwood – to develop a pipeline of soluble guanylate cyclase (sGC) stimulators – was finalized

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